Researchers from the Queensland University of Technology propose 3D printing tissue-engineered constructs as a graft to assist in nipple reconstruction for women who've undergone a mastectomy.
Researchers from Queensland University of Technology, Brisbane are proposing using 3D printing to improve outcomes in mastectomies.
They suggest doing this by creating tissue-engineered constructs to use as a graft in nipple reconstruction for women who have undergone a mastectomy.
In the US, there is a one in eight chance that a woman will develop breast cancer in her lifetime. Many women who are diagnosed or are at high-risk of the disease choose to have a mastectomy. As a result, nipple reconstruction is common, but there is not just one obvious method.
In a paper published in the journal Tissue Engineering, the Australian researchers reviewed the many nipple reconstruction techniques from simple skin flap surgical methods to a modern 3D printed scaffold approach.
They concluded that tissue engineering and regenerative medicine could hugely improve nipple reconstruction and propose a method for 3D printing scaffolds.
“Tissue engineering and regenerative medicine have the potential to dramatically improve current practices regarding nipple reconstruction,” said Louis Calder, Tissue Engineering co-editor-in-chief. ” This review paper provides an invaluable summary of current research and an informative roadmap for future research to improve these reconstruction techniques with innovative biofabrication technologies.”
The article “Nipple Reconstruction: A Regenerative Medicine Approach using 3-D Printed Tissue Scaffolds” was written by Dietmar Hutmacher, of Queensland University of Technology, and colleagues.
It explains that a novel technique which uses 3D printing to create biomaterial scaffolds from multipotent stem cells may already be “technologically possible” to clinically trial.
“A TEC-based approach to nipple reconstruction is now within reach given the recent advancements in biomaterials, additive manufacturing, and lipofilling; however, before clinical trials can commence, further research into the potential carcinogenic effects of ASCs (adipose-derived stem cells) is necessary,” concludes the paper.
For more on 3D printing and advancements in breast cancer care and treatment, check out these stories:
Source: Medical Xpress
License: The text of "Could 3D Printing Tissue Scaffolds Improve Nipple Reconstruction?" by All3DP is licensed under a Creative Commons Attribution 4.0 International License.
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